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AAMC FL3 B/B #39

Posted: Mon May 14, 2018 9:35 pm
by JBike
Hello Next Step,

The answer explanation states that succinyl-CoA Synthetase results in the increased production of succinate. I looked up the chemical equation and I see that this is true. My question is, when it comes to the name "succinyl-CoA Synthetase", what part of that suggests it makes succinate?

Here are my thoughts so far: "Synthetase" obviously means you are synthesizing something. Based on that, I know a new substance is being made. I guess it might be the -CoA part that is confusing me. How does that come into play here? Or, does the -CoA even matter?


Re: AAMC FL3 B/B #39

Posted: Wed May 23, 2018 11:25 am
by NS_Tutor_Bryan
Hey Justin,

This is one of those enzymes you should recognize by name just from memory. It catalyzes a step in the Krebs cycle that's associated with producing a GTP and a CoA, and it's fair game on the MCAT to expect you to basically have completely memorized the Krebs cycle.

- Bryan