NS FL 9 biochem q

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NS FL 9 biochem q

Post by khadeja » Tue Apr 17, 2018 3:15 pm

We are told that SAgs activate T-cell receptors, which you should recognize as relying classically on tyrosine kinase pathways for activation (I is true).

^^ why do T cells rely on tyrosine kinase pathways? how should we know/recognize that?
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Re: NS FL 9 biochem q

Post by NS_Tutor_Andrew » Tue Apr 17, 2018 7:00 pm

Hi khadeja,

Yeah, I think this goes beyond what you need to know as outside knowledge. It might be worth knowing something about tyrosine kinase in the context of cancer, which is kind of a gray area for MCAT knowledge where they technically require fairly minimal knowledge but going beyond that can be helpful for passages, etc., but as is often the case, the first part of the Wikipedia article should suffice. I think the passage may be hinting at this fact by stating that SAgs are mitogens (that is, substances that trigger mitosis), but that's a pretty oblique hint at best. I'll put this on the list of FL questions for us to revise. Thanks for the question!
Andrew D.
Content Manager, Next Step Test Prep.
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