NS FL6 B/B #36

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NS_Tutor_Will
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Joined: Fri May 25, 2018 9:15 am

NS FL6 B/B #36

Post by NS_Tutor_Will » Mon Aug 20, 2018 9:40 am

A student recently stated, "The passage states that combination of the 4 bile acids with the glycine and taurine produce bile SALTS while the question asks about bile ACIDS."

When bile acids are conjugated with taurine or glycine and then form a salt with Na+ or K+, they are called bile salts. Because the conjugation with glycine/taurine lowers the pKa of the bile acid, they are more often in the deprotonated state and so can dissolve more easily. Bile salts are still bile acids, we just use the term bile salt to highlight their lower pKa and typical deprotonated state.

Hope this helps!
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